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Posted on: Aug 28, '08

Haemoglobin Electrophoresis (Hb varient)

Haemoglobin Electrophoresis

HPLC is a relatively fast and accurate method with high precision, and provides precise quantification of Hb A2 and
Hb F. The most commonly occurring Hb variants are Hb- D,S,C and E, along with beta-Thalassemia.

Thalassemia, a hereditary disorder causes defective production of hemoglobin. There are two types, alpha-Thalassemia
and beta-Thalassemia. A frequently occurring, beta-Thalassemia is commonly found in the heterozygous state as minor
or trait. Clinical identification of these carriers is important though sometimes the patients are afflicted with a
mild anemia or may be asymptomatic but any offspring between individuals with the beta-Thalassemia trait are at risk
of being homozygous for the beta-Thalassemia gene. The homozygous state, beta-Thalassemia major, is a lethal disease.

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CancerSA said:

Thanks for sharing!

August 30, '08

manocarla said:

very nice

August 29, '08

VintageWine48 said:
I've heard of thalassemia but I really got to completely understand its variants thanks to you. Keep up the good work. Great post.

August 28, '08